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Limit for Microbial Contamination ¥—ß· ¥ß „π à«π¢ÕߢâÕ°”Àπ¥„π°“√§«∫§ÿ¡ª√‘¡“≥

‰«â„πμ“√“ß∑’Ë 4 à«πÕߧ尓√Õπ“¡—¬‚≈°‰¥â·π–π” “√ªπ‡ªóôÕπ·≈– “√μ°§â“ß„π¬“ ¡ÿπ‰æ√ ´÷Ëßμ”√“
«‘∏’°“√μ√«® Õ∫ª√‘¡“≥°“√ªπ‡ªóôÕπ®ÿ≈‘π∑√’¬å‰«â„π ¡“μ√∞“𬓠¡ÿπ‰æ√‰∑¬‰¥â¡’¢âÕ°”Àπ¥„π‡√◊ËÕß “√
2
Annex 5: Determination of microorganisms æ‘…‚≈À–Àπ—° °“√ªπ‡ªóôÕπ®ÿ≈‘π∑√’¬å ·≈– “√
®–‡ÀÁπ‰¥â«à“¬“‡μ√’¬¡ ”À√—∫„™â¿“¬„π„π°≈ÿà¡∑’Ë μ°§â“ß®“° “√°”®—¥»—μ√Ÿæ◊™ ‡∑à“π—Èπ‚¥¬¬—߉¡à¡’¢âÕ
1, 2 ·≈– 4 μâÕßμ√«®‰¡àæ∫‡™◊ÈÕ Escherichia coli °”Àπ¥°“√§«∫§ÿ¡°“√ªπ‡ªóôÕπ “√æ‘…®“°‡™◊ÈÕ√“
·≈– Salmonella spp. ´÷Ë߇ªì𠓇Àμÿ¢Õß°“√‡°‘¥ Õ–ø≈“∑Õ°´‘π ´÷Ë߇ªìπ “√∑’Ë¡’§«“¡‡ªìπæ‘…·≈–¡’

Õ“°“√∑âÕß√à«ßÕ¬à“ß√ÿπ·√ß à«π¬“‡μ√’¬¡ ”À√—∫∑“ ‚Õ°“ ªπ‡ªóôÕπ„π ¡ÿπ‰æ√ Ÿß ·≈–¡’¢âÕ¡Ÿ≈°“√
·≈–„™â¿“¬πÕ°„π°≈ÿà¡∑’Ë 1 ·≈– 3 μâÕßμ√«®‰¡àæ∫ »÷°…“∑’Ëæ∫°“√ªπ‡ªóôÕπ “√æ‘…®“°‡™◊ÈÕ√“ „π
20
‡™◊ÈÕ Pseudomonas aeruginosa ·≈– Staphylo- º≈‘μ¿—≥±å¬“ ¡ÿπ‰æ√„πª√–‡∑»‰∑¬ ¥—ßπ—Èπ‡æ◊ËÕ„Àâ
coccus aureus ´÷Ë߇ªì𠓇Àμÿ¢Õß°“√‡°‘¥º‘«Àπ—ß ¡ÿπ‰æ√‰∑¬¡’§ÿ≥¿“扥⡓μ√∞“π “°≈ ¡’§«“¡
Õ—°‡ ∫ ‡°‘¥Ωï ÀπÕß à«π Clostridium spp. ´÷Ëß ª≈Õ¥¿—¬μàÕºŸâ∫√‘‚¿§ ·≈– Õ¥§≈âÕß°—∫¢âÕ°”Àπ¥
‡ªìπ‡™◊ÈÕ∑’ËÕ—πμ√“¬¡“° “¡“√∂ √â“ß “√æ‘…ª√–‡¿∑ ¢ÕßÕߧ尓√Õπ“¡—¬‚≈° ®÷ߧ«√‡æ‘Ë¡‡μ‘¡¢âÕ°”Àπ¥

neurotoxin ∑’Ë∑”≈“¬√–∫∫ª√– “∑ ∑”„Àâ¡Õ߇ÀÁπ ¡“μ√∞“π°“√ªπ‡ªóôÕπ “√æ‘…®“°‡™◊ÈÕ√“Õ–ø≈“-
¿“æ´âÕ𠇪ìπÕ—¡æ“μ ·≈–쓬‰¥â ¥—ßπ—Èπ®÷ßμâÕß ∑Õ°´‘π¥â«¬
μ√«®‰¡àæ∫„𬓇μ√’¬¡°≈ÿà¡∑’Ë 2, 3 ·≈– 4 ´÷Ëß
¢âÕ°”Àπ¥π’È Õ¥§≈âÕß°—∫¢âÕ°”Àπ¥¢ÕßÕߧ尓√
‡Õ° “√Õâ“ßÕ‘ß
2,3,18
Õπ“¡—¬‚≈°
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medicinal plant meterials. Geneva: WHO Press; 1998. p.
¢âÕ √ÿª
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°“√§«∫§ÿ¡ª√‘¡“≥ “√ªπ‡ªóôÕπ·≈– “√μ°§â“ß
quality of herbal medicines with reference to contaminants
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„À≥⡓μ√∞“π·≈–¡’§«“¡ª≈Õ¥¿—¬μàÕºŸâ∫√‘‚¿§
¡“μ√∞“𬓠¡ÿπ‰æ√‰∑¬. «“√ “√ ¡ÿπ‰æ√. 2547;11(1):21-
°“√§«∫§ÿ¡§ÿ≥¿“楗߰≈à“« “¡“√∂°√–∑”‰¥âμ—Èß·μà 32.
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‡√‘Ë¡μâπ°√–∫«π°“√º≈‘μæ◊™ ¡ÿπ‰æ√ ‡™àπ °“√‡æ“–
Thai Herbal Pharmacopoeia, Vol. III. Bangkok: Office of
ª≈Ÿ°μâÕߪؑ∫—μ‘μ“¡À≈—°‡°≥±å 燰…μ√¥’∑’ˇÀ¡“– ¡é National Buddishm Press; 2009. p. 5, 162-9.
(Good Agriculture Practice À√◊Õ GAP)é °“√ 5. Hutton M. Human health concerns of lead, mercury,
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‡°Á∫‡°’ˬ«μâÕߪؑ∫—μ‘μ“¡À≈—°‡°≥±å ç°“√‡°Á∫‡°’ˬ«¥’
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°“√º≈‘μμâÕߪؑ∫—μ‘μ“¡À≈—°‡°≥±å ç°√–∫«π°“√
6. Department of Medical Sciences, Ministry of Public Health.
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º≈‘μ∑’Ë¥’ (Good Manufacturing Practice)é ‘Ëß Thai Pharmacopoeia II. Bangkok: Office of National