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¥—ß°≈à“«‰¥â√–∫ÿ‡√◊ËÕß°“√ ÿà¡μ—«Õ¬à“ß “√‡§¡’∑’Ë„™â ¥’¥’∑’ (DDT), ¥’≈¥√‘π (dieldrin), ‡Õπ‚¥´—≈·øπ (en-
‡§√◊ËÕß¡◊Õ °“√ª√–‡¡‘𧫓¡∂Ÿ°μâÕߢÕß«‘∏’«‘‡§√“–Àå dosulfan), ‡Œªμ–§≈Õ√å (heptachlor) œ≈œ “√°≈ÿà¡
§ÿ≥¿“æ·≈–ª√‘¡“≥ ·≈–¡“μ√∞“π°“√ ªπ ÕÕ√å°“‚πøÕ øÕ√— (organophosphorus) ‰¥â·°à
‡ªóôÕπ¬“¶à“·¡≈ß ∑—Èßπ’È À“°‰¡à¡’°“√°”Àπ¥§à“ §≈Õ√å‰æ√‘øÕ (chlorpyrifos), ‰¥§≈Õ√åπÕ
¡“μ√∞“π‰«â„π¡Õ‚π°√“ø ª√‘¡“≥ “√°”®—¥»—μ√Ÿæ◊™ (dichlornos), æ“√“‰∑ÕÕπ (parathion), ¡“≈“‰∑-
∑’ˬա„Àâ¡’‰¥â (¡‘≈≈‘°√—¡/°‘‚≈°√—¡) ®–· ¥ß‰«â„πμ“√“ß ÕÕπ (malathion) ‡ªìπμâπ “√°≈ÿࡧ“√å∫“√凡μ (car-
‚¥¬„πμ”√“¡“μ√∞“𬓠¡ÿπ‰æ√‰∑¬‰¥â°”Àπ¥ bamate) ‡™à𠧓√å∫“√å√‘≈ (carbaryl), §“√å‚∫øŸ·√π
¡“μ√∞“π°“√ªπ‡ªóôÕπ “√°”®—¥»—μ√Ÿæ◊™‰«â®”π«π (carbofuran) ·≈– “√°≈ÿà¡ ‰æ√’∑√Õ¬¥å (pyrethroid)
33 ™π‘¥ °√≥’‰¡à¡’§à“¡“μ√∞“π√–∫ÿ‰«â„πμ“√“ß°Á„Àâ ‡™à𠇥≈쓇¡∑√‘π (deltamethrin), ‡ªÕ√凡∑√‘π
§”π«≥®“° Ÿμ√ (permethrin), ‰´‡ªÕ√凡∑√‘π (cypermethrin) œ≈œ
ADI × M „π°“√μ√«®«‘‡§√“–Àå “√°”®—¥»—μ√Ÿæ◊™¥—ß°≈à“«„™â«‘∏’
MDD × 100 ·°Á ‚§√¡“‚∑°√“øøï (gas chromatography)
‡¡◊ËÕ ‚¥¬„™â carbophenothion ‡ªìπ internal standard
ADI = ¢π“¥∑’ˬա√—∫‰¥âμàÕ«—π (accept- ·≈–‡ª√’¬∫‡∑’¬∫§à“ relative retention time
able daily intake) ∑’Ë°”À𥂥¬ FAO - WHO ¢Õßμ—«Õ¬à“ß°—∫§à“∑’Ë°”À𥉫â„πμ“√“ß ”À√—∫ “√
„πÀπ૬¡‘≈≈‘°√—¡μàÕ°‘‚≈°√—¡πÈ”Àπ—° °”®—¥»—μ√Ÿæ◊™·μà≈–™π‘¥·≈–§”π«≥ª√‘¡“≥¢Õß “√
M = πÈ”Àπ—°„πÀπ૬°‘‚≈°√—¡ (60 °‘‚≈°√—¡) °”®—¥»—μ√Ÿæ◊™‰¥â®“°æ◊Èπ∑’Ë„μâæ’§ (peak area) ¢Õß
MDD = ¢π“¥¢Õß ¡ÿπ‰æ√∑’ˉ¥â√—∫„π πÈ”¬“μ—«Õ¬à“߇ª√’¬∫‡∑’¬∫°—∫æ◊Èπ∑’Ë„μâæ’§¢Õß “√
2,4
Àπ÷Ëß«—π (daily dose of the plant material in °”®—¥»—μ√Ÿæ◊™„ππÈ”¬“¡“μ√∞“π
kilograms)
°“√μ√«® Õ∫°“√ªπ‡ªóôÕπ®ÿ≈‘π∑√’¬å (Microbial
„π°√≥’∑’Ë ¡ÿπ‰æ√π—ÈπÕ¬Ÿà„π√Ÿª·∫∫ “√ °—¥
contamination)
∑‘߇®Õ√åÀ√◊Õ√Ÿª·∫∫Õ◊ËπÊ „À⧔π«≥§à“¡“μ√∞“π
®“° Ÿμ√ °“√ªπ‡ªóôÕπ¢Õ߇™◊ÈÕ®ÿ≈‘π∑√’¬å„𬓠¡ÿπ‰æ√
ADI × M × E Õ“®°àÕ„À⇰‘¥‚√§„π¡πÿ…¬å‰¥â ¥—߇™àπ√“¬ß“π°“√
MDD × 100 ‡ ’¬™’«‘μ®“° listeriosis ®“°°“√‰¥â√—∫¬“‡¡Á¥ alfalfa
E = extraction factor ¢Õß«‘∏’‡μ√’¬¡¬“ ∑’Ë¡’°“√ªπ‡ªóôÕπ‡™◊ÈÕ·∫§∑’‡√’¬°√—¡∫«° listeria
15
®“°æ◊™ ¡ÿπ‰æ√ (extraction factor of the method monocytogenes ∑—Èßπ’È‚¥¬ª°μ‘·≈â« ¡ÿπ‰æ√®–¡’
of preparation, determined experimentally) ®ÿ≈‘π∑√’¬åªπ‡ªóôÕπ‚¥¬∏√√¡™“μ‘ ‡™àπ ®“°¥‘π ¡Ÿ≈ —μ«å
Õߧ尓√Õπ“¡—¬‚≈°·≈–μ”√“¡“μ√∞“𬓠¡ÿπ ·≈–¬—ßÕ“®ªπ‡ªóôÕπ√–À«à“ß°“√¢π àß °“√‡°Á∫√—°…“
2
‰æ√‰∑¬‰¥â·π–π”„Àâμ√«®À“ª√‘¡“≥ “√μ°§â“ß®“° ∑’ˉ¡à∂Ÿ° ÿ¢≈—°…≥– √“¬ß“π°“√«‘®—¬∑’ˉ¥â∑”°“√μ√«®
“√°”®—¥»—μ√Ÿæ◊™„π ¡ÿπ‰æ√∑’Ë ”§—≠ 4 ª√–‡¿∑ §◊Õ «‘‡§√“–À嬓·ºπ‚∫√“≥„π™à«ßªï æ.». 2539-2541
“√°≈ÿà¡ ÕÕ√å°“‚π§≈Õ√å√’π (organochlorine) ‡™àπ ®”π«π 211 μ—«Õ¬à“ß æ∫¬“·ºπ‚∫√“≥∑’Ë¢÷Èπ∑–‡∫’¬π