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J Thai Trad Alt Med Vol. 21 No. 3 Sep-Dec 2023 519
Table 1 Basic characteristics of patients
Characteristics TA group (n = 10) CHI-CUR group (n = 9) P
Age (Year)(mean ± SD) 56.3 ± 6.4 49.1 ± 13.7 0.16
Sex (Female/Male) 8/2 9/0 0.47
Underlying diseases (Yes/No) 5/5 4/5 1.00
Hyperlipidemia 1 4
Hypertension 3 0
Diabetes mellitus 1 0
History of OLP (Yes/No) 6/4 5/4 1.00
Smoking (Yes/No) 0/10 0/9 -
Drinking (Yes/No) 1/9 1/8 1.00
Type of OLP (n)
Mild/marked erythema 6 8 0.09
Ulceration 3 1 0.58
Non-erosive reticular 1 - -
Pain (median) 2(0-9) 3(0-7) 0.60
Dryness (median) 1(0-2) 1(0-4) 0.69
3
3
No of C. albicans colonies 0.7 5 10 ± 0.4 5 10 1.2 5 10 ± 1.2 5 10 3
3
(CFU/ml)(mean ± SE) (n = 8/10) (n = 7/9) 0.69
SD = Standard deviation SE = Standard error of mean
TA = 0.1% triamcinolone acetonide mouthwash
CHI-CUR = 0.1% alcohol-free chitosan-curcuminoids mouthwash
p < 0.05 comparison of different mouthwash groups
of the CHI-CUR-treated group included only marked erythema. High concentrations of C.
those patients who adhered to the protocol albicans colonies were found before the treat-
(n = 9). The remaining 9 patients in the 0.1% ment in 8 out of 10 (80%) patients receiving
CHI-CUR-treated group were female. Only 2 TA mouthwash and 7 out of 9 (77.8%) patients
patients included in the clinical study were receiving CHI-CUR mouthwash. The number
male and both were in the TA-treated group. of C. albicans colonies was not significantly
Patient ages ranged from 35-63 years old. The different from each other.
base line characteristics on underlying dis- Both treatment groups had a comparable
ease, history of having OLP, smoking, drinking, time to remission state within the 4-week
activity score, pain level and the dryness of the treatment course and a comparable efficacy in
oral cavity for both groups were not signifi- relief of pain or dryness of the oral cavity within
cantly different from each other. Most of the the 2-week treatment course as shown in Table
patients in both treatment groups had mild/ 2. Seven out of 9 (77.8%) patients using CHI-
