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J Thai Trad Alt Med                                    Vol. 21  No. 3  Sep-Dec  2023  507




                                                                                 Editor’s Note



            Editor’s Note







                 At present, the situation of COVID-19   second article, Randomized-Controlled Trial
            pandemic has improved considerably, but     to Compare the Efficacy of Andrographis

            the global warming has been so worsening    paniculata Powder and Favipiravir for the
            that the United Nations Secretary-General   Treatment of Mild COVID-19, is a high-quality
            has deemed that it has become “Global       and reliable study compared with other herbal

            boiling’’. Moreover, the wars as well as internal   clinical studies. But there are some limitations,
            conflicts have been more violent especially   including: (1) Thailand has got favipiravir

            those between Russia and NATO members,      indicated as a “standard therapy’’ despite its
            Israel and the Gaza Strip (beginning on 7   lack of adequate “evidence’’. So, it is difficult
            October 2023), and the Myanmar military and   for this kind of research to use a placebo in

            anti-government groups along the western    the control group; and the difference is hard
            border of Thailand. The Thai economy that   to be measured. (2) COVID-19 is an emerging
            has been recovering from the COVID-19 crisis   disease. Although academics have gained

            has to face rising challenges – the stock market   much knowledge in a short period of time,
            declining markedly and the new government’s   many issues are still unknown. Importantly, the
            economic stimulation measures not being so   virus has been mutating all the time, resulting

            hopeful. However, our journal is still making   in difficulties in measuring the differences.
            continuous development efforts.             (3) The knowledge about the action mecha-

                 In this issue, the journal has twelve   nism of A. paniculata (commonly known in
            original articles. The first one, Efficacy of   Thai as fa thalai chon) is very limited, result-
            0.1% Chitosan-Curcuminoid Mouthwash         ing in difficulties in making discussions and

            in Treatment of Oral Lichen Planus and      conclusions of the study results. Moreover,
            Prevention of Disease Relapse, covers the   there are other limitations regarding the study

            results of its Phase 2 study in 20 participants   products in terms of Good Agricultural Prac-
            showing the clear efficacy of the product; so   tice (GAP) and Good Manufacturing Practice
            a Phase 2 study should be conducted. The    (GMP) and Good Clinical Practice (GCP),
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