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268 วารสารการแพทย์แผนไทยและการแพทย์ ทางเลือก ปีที่ 18 ฉบับที่ 2 พฤษภาคม-สิงหาคม 2563

folk medicine recommendation that the decoc- port the observations by Thai folk medicine
tion from T. triquetrum leaves can be used to practitioners that T. triquetrum extract has
improve sexual and physical performance. Im- antimicrobial activity. [1,8-9] Previous research

proved sexual and physical performance may has also reported pathogenic bacteria growth
be facilitated by PDE-5 inhibitory activity [14,18-20] inhibited by T. triquetrum extract. In our
[25]
experienced by patients taking a decoction of study, the polar extracts (water and ethanolic)
T. triquetrum leaves. of T. triquetrum inhibited bacterial growth.
Antioxidant activity is often used to We also found that non-polar extract (hexane)

screen for promising medicinal compounds suppressed fungal growth. Our results suggest
or herbs because free radicals are associated that T. triquetrum could be a promising anti-

with many diseases. We interpret low IC50 microbial agent.
and TEAC values as showing that a compound
effectively scavenges free radicals. In our Conclusion
[16]
study, water extract of T. triquetrum presented According to the results of the current
the highest antioxidant activity with the low- study, T. triquetrum is a promising herb for
est IC50 and lowest TEAC of all the types of ex- health care product development. It could be

tract. Our finding supports the theory that an- developed as a product for health promotion
tioxidant activity of T. triquetrum extract may or an alternative antimicrobial agent. Because
explain the effectiveness of T. triquetrum Thai our results show the beneficial effects for in

folk medicine formulations. Thai folk medi- vitro experiments, we recommend that in vivo
[21]
cine practitioners have promoted the boiled studies and clinical studies be carried out in

leaf of T. triquetrum as a health promotion the future.
beverage. The presence of free radicals is an
[1,8]
important risk factor for several non-infectious Acknowledgment

diseases and organ degeneration. [22-23] Taking The study was supported with the grant
T. triquetrum and thus reducing free radicals by Sirindhorn College of Public Health, Phit-

may improve and promote consumer health. sanulok research fund.
Moreover, T. triquetrum extract possessing
References
hepatoprotective activity and capability to
[24]
1. Vedpal D, Jayaram U, Wadhwani A, Dhanabal SP. Isola-
increase glucose consumption are benefit to tion and characterization of flavonoids from the roots of
[12]
patients who expect to promote their health. medicinal plant Tadehagi triquetrum (L.) H.Ohashi. Nat
Prod Res. 2019:1-6.
In addition, our experimental results sup- 2. Satean G, Homhuan S, Premprasit S. Plant utilization