Page 113 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 3 ฉบับที่ 3

P. 113

«“√ “√°“√·æ∑¬å·ºπ‰∑¬·≈–·æ∑¬å∑“ß‡≈◊Õ° ªï∑’Ë Û ©∫—∫∑’Ë Û ¡‘∂ÿπ“¬π -°—π¬“¬π ÚıÙ¯ 111

µ“√“ß∑’Ë 7 º≈°“√µ√«®Õ«—¬«–∑“ß®ÿ≈æ¬“∏‘«‘∑¬“¢ÕßÀπŸ·√∑‡æ»ºŸâ∑’Ë‰¥â√—∫ “√ °—¥‡¡≈Á¥§”· ¥‡ªìπ

‡«≈“ 28 «—π

Dose of Bixa orellana extract (mg/kg /day)

Organs Microscopic control 0.24 2.4 12 60

findings n = 15 n = 15 n = 15 n = 15 n = 15
Lung Lymphoid 7/15 9/15 5/15 10/15 13/15

proliferated
bronchiole
Heart Myocardiosis 0/15 1/15 0/15 1/15 1/15

Liver Hepatocyte 0/15 0/15 315 2/15 5/15*
Fatty degeneration
Pancreas Acinar hyperplasia 0/15 0/15 0/15 0/15 1/15

Small GALT 2/15 2/15 0/15 3/15 1/15
intestine proliferation
Large GALT 3/15 2/15 5/15 4/15 4/15

intestine proliferation
Adrenal Cortex fatty 0/15 0/15 0/15 3/15 0/15
gland degeneration

*·µ°µà“ß®“°°≈ÿà¡§«∫§ÿ¡Õ¬à“ß¡’π—¬ ”§—≠∑“ß ∂‘µ‘ (p<0.05)

º≈°“√µ√«®· ¥ß„π√Ÿª¢Õß ®”π«πÀπŸ∑’Ëæ∫°“√‡ª≈’Ë¬π·ª≈ß/®”π«πÀπŸ∑’Ëµ√«®
GALT=Gut associated lymphoid tissue

108 109 110 111 112 113 114 115 116 117 118