Page 33 - วารสารปีที่16ฉบับที่2

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ºŸâ√—∫º‘¥™Õ∫∫∑§«“¡: patamaporn.p@dmsc.mail.go.th

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∑Õßæ—π™—Ëß ‡ªìπ ¡ÿπ‰æ√∑’Ë„™â„π∑“ß°“√·æ∑¬å·ºπ‚∫√“≥¢Õ߉∑¬‡æ◊ËÕ°“√√—°…“‚√§º‘«Àπ—ß ·≈–º◊Ëπ§—π
°“√∑¥ Õ∫ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“¢Õßæ◊™π’È æ∫«à“¡’ƒ∑∏‘Ï¥’μàÕ°“√μâ“π‡™◊ÈÕ√“°≈ÿࡇ¥Õ√å¡“‚μ‰øμå´÷Ë߇ªì𠓇ÀμÿÀ≈—°¢Õß
‚√§º‘«Àπ—ß®“°‡™◊ÈÕ√“ °“√»÷°…“π’È¡’‡ªÑ“À¡“¬‡æ◊ËÕ∑¥ Õ∫ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“¢Õß “√ °—¥®“° à«πμà“ß Ê ¢Õß∑Õßæ—π™—Ëß
·≈–«‘‡§√“–Àåª√‘¡“≥ “√ ”§—≠∑’Ë¡’ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“¢Õß “√ °—¥·μà≈–™π‘¥‡æ◊ËÕæ—≤π“«‘∏’ °—¥∑’Ë∑”„À≥⠓√μâ“π
‡™◊ÈÕ√“„πª√‘¡“≥ Ÿß ‚¥¬π” à«π„∫ ≈”μâπ ·≈–√“°·ÀâߢÕß∑Õßæ—π™—Ëß¡“ °—¥¥â«¬‡Õ∑“πÕ≈‚¥¬«‘∏’°“√À¡—°·≈–
°—¥¥â«¬§≈◊ËπÕ—≈μ√“‚´π‘§ ®“°π—Èπ∑¥ Õ∫ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“¢Õß “√ °—¥μàÕ‡™◊ÈÕ°≈ÿࡇ¥Õ√å¡“‚μ‰øμå∑’ˇªì𠓇Àμÿ
¢Õß‚√§º‘«Àπ—ß®“°‡™◊ÈÕ√“ 3 ™π‘¥ (Trichophyton rubrum, Trichophyton mentagrophytes ·≈– Microsporum
gypseum) ‚¥¬«‘∏’ broth microdilution method ·≈–π” “√ °—¥·μà≈–™π‘¥¡“«‘‡§√“–Àå≈“¬æ‘¡æåπ‘È«¡◊Õ‚§√¡“‚∑-
°√“ø·∫∫¢Õ߇À≈« ¡√√∂π– Ÿß °“√∑¥ Õ∫ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“°≈ÿࡇ¥Õ√å¡“‚μ‰øμå¢Õß∑Õßæ—π™—Ëßæ∫«à“ “√ °—¥
®“° à«π√“°¡’ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“¥’∑’Ë ÿ¥„π°“√μâ“π‡™◊ÈÕ√“∑’Ë„™â∑¥ Õ∫ °“√·¬° “√∫√‘ ÿ∑∏‘Ï·≈–«‘‡§√“–Àå Ÿμ√
‚§√ß √â“ß∑“߇§¡’æ∫ “√ rhinacanthins B, C, N ·≈– Q ‡ªìπ “√ ”§—≠∑’Ë¡’º≈„π°“√ÕÕ°ƒ∑∏‘Ï πÕ°®“°π’È “√
°—¥‡Õ∑“πÕ≈¢Õß√“°∑Õßæ—π™—Ëß∑’Ëπ”¡“ °—¥·¬°μàե⫬‡Õ∑‘≈Õ–´‘‡μ∑„Àâª√‘¡“≥ “√°≈ÿà¡ rhinacanthins √«¡∑’Ë Ÿß¢÷Èπ
·≈–¡’ƒ∑∏‘Ï°“√μâ“π‡™◊ÈÕ√“¥’‡∑’¬∫‡∑à“°—∫ rhinacanthin C ( “√ÕÕ°ƒ∑∏‘ÏÀ≈—°„π°“√μâ“π‡™◊ÈÕ√“) ¥—ßπ—Èπ«‘∏’°“√ °—¥
¥—ß°≈à“«π’È®÷߇ªìπÕ’°«‘∏’°“√Àπ÷Ëß∑’Ëπà“®–‡À¡“– ¡ ”À√—∫°“√‡μ√’¬¡ “√ °—¥√“°∑Õßæ—π™—Ë߇æ◊ËÕ𔉪æ—≤𓇪ìπ
μ”√—∫º≈‘μ¿—≥±å ¡ÿπ‰æ√μâ“π‡™◊ÈÕ√“‰¥âμàÕ‰ª

§” ”§—≠: ∑Õßæ—π™—Ëß, μâ“π‡™◊ÈÕ√“, ‡¥Õ√å¡“‚μ‰øμå, ‰√π“·§π∑‘π

Received date 19/07/17 Accepted date 22/06/18

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