Page 30 - วารสารปีที่15ฉบับที่1

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μ“√“ß∑’Ë 6 ª√‘¡“≥øïπÕ≈‘°√«¡·≈–ª√‘¡“≥‡ø≈‚«πÕ¬¥å√«¡¢Õß “√ °—¥μà“ß Ê

Total phenolic content Total flavonoid content
Sample
(μg GAE/g dry weight) (μg QE/g dry weight)

acetone 952.84 ± 128.75 567.55 ± 14.43
ethanol 1339.31 ± 31.23 618.34 ± 38.20
water 870.78 ± 48.55 256.47 ± 13.13
hot water 1770.49 ± 20.60 178.86 ± 5.08

[27]
Àπ—°ºßÀ≠â“·Àâß ‡¡◊ËÕ‡∑’¬∫°—∫ “√ quercetin ¡’§à“ 32 μg/ml) ·≈– Candida albicans (IC 17.6
50
Ÿß ÿ¥„π “√ °—¥ ethanol ´÷Ëß¡’§à“‡∑à“°—∫ 618.34 μg μg/ml) μâ“π‡™◊ÈÕ Plasmodium falciparum (IC 50
QE μàÕ “√ °—¥·Àâß 1 °√—¡ ¥—ß· ¥ß„πμ“√“ß∑’Ë 6 3.70 μg/ml) ·≈– antimycobacterial activity
[28]
(MIC 50 μg/ml) ¢âÕ¡Ÿ≈æ√’§≈‘π‘°¢Õß “√ 4-
Õ¿‘ª√“¬º≈
coumaric acid æ∫«à“¡’ƒ∑∏‘Ϭ—∫¬—Èß°“√‡°“–μ—«¢Õß
°“√À“ª√‘¡“≥ “√ °—¥„πμ—«∑”≈–≈“¬ æ∫«à“ ‡°≈Á¥‡≈◊Õ¥ (antiplatelet activity) ®“°°“√‡Àπ’ˬ«

‡¡◊ËÕ °—¥¥â«¬πÈ”®–¡’ª√‘¡“≥ “√ °—¥ Ÿß∑’Ë ÿ¥¡“° π”‚¥¬ ADP (ADP-induced platelet aggre-
[29]
°«à“°“√ °—¥¥â«¬μ—«∑”≈–≈“¬™π‘¥Õ◊Ëπ æ∫«à“‡ªìπ gation) ‚¥¬‰¡à àߺ≈μàÕ°“√·¢Áßμ—«¢Õ߇≈◊Õ¥
“√„π°≈ÿà¡¡’¢—È« ‰¥â·°à phenolic compounds ·≈– πÕ°®“°π’È¡’ƒ∑∏‘ϪÑÕß°—π°“√°√–μÿâπ°“√∑”≈“¬ DNA

flavonoids ‡¡◊ËÕ‡ª√’¬∫‡∑’¬∫ª√‘¡“≥ phenolics ·≈– ¢Õ߇´≈≈å°√–®°μ“°√–μà“¬∑’Ë∂Ÿ°°√–μÿâπ¥â«¬· ß UV-
flavonoids „π “√ °—¥∑’Ë„™âμ—«∑”≈–≈“¬∑’Ë¡’¢—È«ª“π B ´÷Ëß°“√¬—∫¬—Èßπ’ÈÕ“®ºà“π∑“ß°≈‰°μâ“πÕπÿ¡Ÿ≈Õ‘ √–
[30]
°≈“ß·≈–πÈ” æ∫«à“ “√ °—¥ ethanol ·≈– “√ °—¥ (free radical scavenging activity) πÕ°®“°
acetone ®–¡’ª√‘¡“≥ flavonoid √«¡ Ÿß°«à“ “√ π’È¡’ƒ∑∏‘Ϫ°ªÑÕß°√–®°μ“®“°°“√°√–μÿâπ°“√∑”≈“¬
[31]
°—¥πÈ” ·μà “√ °—¥®“°πÈ”μâ¡®–¡’ª√‘¡“≥ pheno- ‚¥¬· ß UV-B „π°√–μà“¬¥â«¬
lics Ÿß∑’Ë ÿ¥ ∑—Èß “√°≈ÿà¡ phenolics ·≈– “√°≈ÿà¡ °“√»÷°…“ª√‘¡“≥ “√Õ“À“√¢ÕߺßÀ≠⓬ÿà¡æ∫
[24-25]
flavonoids ¡’ƒ∑∏‘Ïμâ“πÕπÿ¡Ÿ≈Õ‘ √– à«π “√ «à“¡’ª√‘¡“≥„¬Õ“À“√√«¡‰¢¡—π ·≈–‚ª√μ’π√âÕ¬≈–
∫√‘ ÿ∑∏‘Ï∑’Ë·¬°‰¥â®“°°√–∫«π°“√∑“ß‚§√¡“‚∑°√“øï 71.87, 0.25 ·≈– 9.08 μ“¡≈”¥—∫ ‡¡◊ËÕ«‘‡§√“–Àå¥â«¬

‰¥â·°à 5,7,4'-trimethoxyflavone ·≈– 4-coumaric HPLC æ∫°√¥Õ–¡‘‚π 18 ™π‘¥ ‡™àπ aspartic acid,
acid glutamic acid ·≈– leucine √«¡∂÷ß«‘μ“¡‘πμà“ß Ê
°“√»÷°…“°“√ÕÕ°ƒ∑∏‘Ï¢Õß “√ 5,7,4'- ‰¥â·°à «‘μ“¡‘π‡Õ, «‘μ“¡‘π∫’1, «‘μ“¡‘π∫’2, ·≈–«‘μ“¡‘πÕ’

trimethoxyflavone æ∫«à“¡’ƒ∑∏‘Ïμâ“π‡™◊ÈÕ·∫§∑’‡√’¬ °“√«‘‡§√“–Àåª√‘¡“≥·√à∏“μÿ¥â«¬ XRF (X-Ray Fluo-
‰¥â·°à Staphylococcus aureus, Pseudomonas rescence) „πºßÀ≠⓬ÿà¡·Àâß “√ °—¥‡Õ∑“πÕ≈

aeruginosa, Escherichia coli ¡’§à“ MIC 128 μg/ ·≈– “√ °—¥πÈ”μâ¡¢ÕßÀ≠⓬ÿà¡ ‚¥¬· ¥ßº≈‡ª√’¬∫
[26]
ml ¡’ƒ∑∏‘Ïμâ“π‡™◊ÈÕ√“ Candida krusei (MIC ‡∑’¬∫°—∫ºß°≈⫬πÈ”«â“·Àâß·≈–ºß°≈⫬ÀÕ¡·Àâß
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