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Volume Calibration of çTha-Nané and the Effects in the Efficacy of Drugs
Preparation

‡
†
Witchayanee Panngam*, Somchai Suriyakrai , Sakkrarn Sangkhamanon , Suppachai
Tiyaworanant §, #
*Master of Science Program in Thai Traditional Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University,
Khon Kaen 40002, Thailand
†
Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand
‡
Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
§
Department of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University,
Khon Kaen 40002, Thailand
#
Corresponding author: suptiy@kku.ac.th
Abstract

çTha-nané in Thai traditional scriptures was different from çtha-nan luangé, the latter being a unit of
volume equivalent to 1 liter. çTha-nan luangé was used to measure out crude drugs for preparing medicines
instead of traditional çtha-nané, which might affect prepared drugsû efficacy. The objective of this study was
to calibrate the volume of traditional tha-nan and to evaluate the efficacy of wound-healing remedies prepared
using calibrated tha-nan, compared with those prepared using tha-nan luang, in healing excision wounds on
male Spraque-Dawley rats. The calibrated volume of çtha-nané was calculated by multiplying the traditional
çtha-nané size number with 1.548, the converting factor, to obtain the volume in milliliters. The efficacy
evaluation of the prepared wound-healing remedies showed that the oil remedies prepared with crude drugs
measured out using the calibrated tha-nan (NR119/78cv) of 929 milliliters based on çtha-nan 600é and the
balm remedy prepared with crude drugs measured out using the calibrated tha-nan (WP255/2cv) of 1,285
milliliters based on çtha-nan 830é were more efficacious than those prepared with crude drugs measured out
using tha-nan luang.

Key words: Tha-nan, Tha-nan Luang, calibration volume

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