Page 11 - วารสารปีที่15ฉบับที่1

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«à“§◊Õ ·Õ≈ø“-·´π∑“≈Õ≈ „™â‡∑§π‘§μà“ß Ê ∑“ß “√‡∑’¬∫¡“≈–≈“¬¥â«¬μ—«∑”≈–≈“¬‡¡∑“πÕ≈

‡ª°‚∑√ ‚°ªï ‰¥â·°à Õ‘πø√“‡√¥ ‡ª°‚∑√ ‚°ªï §«“¡‡¢â¡¢âπ¢Õß “√≈–≈“¬¢Õß “√‡∑’¬∫ §◊Õ 0.5
(Nicolet 4700 FT-IR, Thermo electron corpo- ¡‘≈≈‘°√—¡/¡‘≈≈‘≈‘μ√
ration, USA) 𑫇§≈’¬√å·¡°‡πμ‘°‡√‚´·ππ´å 4. √–∫∫¢Õß‚§√¡“‚∑°√“øï·∫∫™—Èπ∫“ß

‡ª°‚∑√ ‚°ªï (Bruker Ultrashield AV300 MHz, À¬¥ “√≈–≈“¬μ—«Õ¬à“ß ®”π«π 20 ‰¡‚§√≈‘μ√
Karlsruhe, Germany) ·≈–·¡ ‡ª°‚∑√ ‚°ªï ·≈– “√≈–≈“¬¢Õß “√‡∑’¬∫ ®”π«π 5 ¡‘≈≈‘≈‘μ√
(6890N GC/5973 MS, EIMS 70 eV, Agilent ¥â«¬‡§√◊ËÕß Linomat 5 (Camag, Switzerland)

Technologies, Germany) ‰¥â¢âÕ¡Ÿ≈¢Õß “√®“° ≈ß∫π·ºàπ‚§√¡“‚∑°√“øï·∫∫™—Èπ∫“ß™π‘¥ alu-
‡∑§π‘§μà“ß Ê ¥—ßπ’È minium sheet silica gel GF 254 (Merck 5554,

·Õ≈ø“-·´π∑“≈Õ≈ (√Ÿª∑’Ë 1) ¡’≈—°…≥–‡ªìπ Germany) ®“°π—Èπ𔉪«“ß„π∂—ß‚§√¡“‚∑°√“øï´÷Ëß
πÈ”¡—π ‰¡à¡’ ’ IR (KBr disc): 3500-3100, 2941, 2872, Õ‘Ë¡μ—«¥â«¬«—Ø¿“§‡§≈◊ËÕπ∑’Ë §◊Õ (1) à«πº ¡¢Õß
-1 1
1455, 1375 cm ; H NMR (300 MHz, CDCl ): ‡Œ°‡´π ‡Õ∑‘≈·Õ´’‡∑μ ·≈–‡¡∑“πÕ≈ „πÕ—μ√“ à«π
3
5.31 (1H, t, J = 7.5 Hz, H-4), 4.14 (2H, s, H-1), 60:30:0.2 À√◊Õ (2) à«πº ¡¢Õ߇Œ°‡´π ‡Õ∑‘≈·Õ´’-
1.98 (2H, m, H-5), 1.79, (3H, s, H-3), 1.70- 1.60 ‡∑μ ‡¡∑“πÕ≈ ·≈–°√¥·Õ´’μ‘° „πÕ—μ√“ à«π

(2H, m, H-11 ·≈– H-13), 1.54 (1H, m, H-12), 60:10:0.2:0.01 À≈—ß®“°«—Ø¿“§‡§≈◊ËÕπ∑’ˇ§≈◊ËÕπ‰ª
1.23 (1H, m, H-6), 1.14 (1H, m, H-6), 1.05 (2H, ∫π«—Ø¿“§§ß∑’ˉ¥â√–¬–∑“ß 8 ‡´π쑇¡μ√ π”·ºàπ
dd, J = 7.5, 9.6, H-11 ·≈– H-13), 0.99 (3H, s, ‚§√¡“‚∑°√“øï·∫∫™—Èπ∫“ßÕÕ°¡“∑‘È߉«â„Àâ·Àâß¿“¬

H-15), 0.83 (2H, s, H-10 ·≈– H-14), 0.83 (3H, s, „μâÕÿ≥À¿Ÿ¡‘ÀâÕß ®“°π—Èπ𔉪μ√«® Õ∫‚¥¬ —߇°μ
13
H-8); C NMR (75 MHz, CDCl ): 133.7 (C-2), ¿“¬„μâ· ßÕ—≈μ√“‰«‚Õ‡≈μ∑’˧«“¡¬“«§≈◊Ëπ 254 ·≈–
3
129.5 (C-4), 61.6 (C-1), 45.9 (C-9), 38.2 (C-12), 366 π“‚π‡¡μ√ ·≈– —߇°μ¿“¬„μâ· ß∏√√¡™“μ‘
34.9 (C-6), 31.5 (C-11 ·≈– C-13), 27.4 (C-7), ¿“¬À≈—ß®“°°“√æàπ¥â«¬πÈ”¬“æàπÕ–π‘´—≈¥’‰Œ¥å
22.9 (C-5), 21.3 (C-3), 19.5 (C-10 À√◊Õ C-14), (anisaldehyde) ·≈â«„À⧫“¡√âÕπ∑’ËÕÿ≥À¿Ÿ¡‘ 100
19.4 (C-10 À√◊Õ C-14), 17.5 (C-15), 10.6 (C-8); Õß»“‡´≈‡´’¬ ‡ªìπ‡«≈“ 5 π“∑’

+
EI-MS m/z: 220 [M] , C H O
15 24
º≈°“√»÷°…“
3. °“√‡μ√’¬¡ “√≈–≈“¬μ—«Õ¬à“ß·≈–
“√≈–≈“¬¢Õß “√‡∑’¬∫ °“√»÷°…“π’ȉ¥â ÿà¡´◊ÈÕμ—«Õ¬à“߇§√◊ËÕ߬“®—π∑πå‡∑»
°“√‡μ√’¬¡ “√≈–≈“¬μ—«Õ¬à“ß ∑”‚¥¬π”ºß 15 μ—«Õ¬à“ß (T1-T15) ·≈–®—π∑πåÀÕ¡ 11 μ—«Õ¬à“ß
¡ÿπ‰æ√®”π«π 500 ¡‘≈≈‘°√—¡ ¡“ °—¥¥â«¬μ—«∑” (H1-H11) ®“°∑—Ë«ª√–‡∑» ∑ÿ°μ—«Õ¬à“ß¡’°≈‘ËπÀÕ¡

≈–≈“¬‡¡∑“πÕ≈®”π«π 2 ¡‘≈≈‘≈‘μ√ ‚¥¬„™â§≈◊Ëπ ‡©æ“– μ—«Õ¬à“ß à«π„À≠à¡’≈—°…≥–‡ªìπ™‘Èπ —∫‡≈Á° Ê
‡ ’¬ß§«“¡∂’Ë Ÿßπ“π 30 π“∑’ ®“°π—Èππ” “√≈–≈“¬ ’πÈ”μ“≈Õ¡‡À≈◊Õß ∫“ßμ—«Õ¬à“ß¡’≈—°…≥–‡ªìπ™‘Èπ

à«π‡Àπ◊Õμ–°Õπ∑’ˉ¥â¡“„™â‡ªìπ “√≈–≈“¬μ—«Õ¬à“ß ·°àπ‰¡â Õ“®¡’ à«π¢Õ߇ª≈◊Õ°μ‘¥Õ¬Ÿà∫â“ß ·≈–¡’Àπ÷Ëß
°“√‡μ√’¬¡ “√≈–≈“¬¢Õß “√‡∑’¬∫ ∑”‚¥¬π” μ—«Õ¬à“ߧ◊Õ ®—π∑πå‡∑»μ—«Õ¬à“ß∑’Ë 14 ∑’Ë¡’≈—°…≥–