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Abstract

Botanical Identification of Chan-thet and Chan-hom Crude Drugs by Thin
Layer Chromatography
‡
,††
*
Sununta Srisopon , Jankana Burana-osot , Uthai Sotanaphun ††,†§
*Medicinal Plant Research Institute, Department of Medical Sciences, Ministry of Public Health,
Nonthaburi 11000, Thailand.
†
Department of Pharmacognosy, Faculty of Pharmacy, Silpakorn University, Nakhon-pathom 73000, Thailand.
‡
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Silpakorn University, Nakhon-pathom 73000, Thailand.
§
Corresponding author: u.sotana@gmail.com
çChan-theté and çchan-homé are crude drugs whose identifications are confusing; so their botani-
cal species should be investigated. Fifteen samples of crude drugs çchan-theté and 11 samples of çchan-
homé were randomly purchased from traditional drugstores throughout Thailand. Their chemical
fingerprints were investigated using the thin layer chromatography method. The results were compared
with authentic samples, and a-santalol purified in our laboratory was used as the chemical marker. The
results indicated that all samples of çchan-theté and 9 samples of çchan-homé possessed a-santalol as
their chemical constituent. Among them, 11, 3 and 1 samples of çchan-theté gave chemical fingerprints
similar to Santalum spicatum, S. album and S. lanceolatum, respectively; whereas 8 and 1 samples of
çchan-homé were similar to those of S. spicatum and S. lanceolatum, respectively. Two other samples of
çchan-homé revealed chemical fingerprints similar to Mansonia gagei. Based on the results, it is con-
cluded that çchan-theté and çchan-homé currently available in traditional drugstores originate from
four different plant species, mostly from the wood of S. spicatum. And the results can be applied for the
quality control of çchan-theté and çchan-homé crude drugs.
Key words: Chan-thet, Chan-hom, Santalum, identification, thin layer chromatography

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