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Journal of Thai Traditional & Alternative Medicine Vol. 9 No. 2 September-December 2011 103
√Ÿª∑’Ë 2 ‚§√¡“‚∑·°√¡¢Õß “√¡“μ√∞“π genistein ‚¥¬„™â«‘∏’ HPLC ‚¥¬„™âπÈ”:Õ–´’‚μ‰π‰μ√≈å ∑’ˇ«≈“ 0 π“∑’ (70:30), 6 π“∑’ (60:40)
·≈– 12 π“∑’ (70:30) peak ¢÷Èπ∑’ˇ«≈“ 5.67 π“∑’
20 ‰¡‚§√≈‘μ√ ·≈– 43+C5 ¡’¢π“¥·§≈≈— ‡©≈’ˬ °«â“ß׬“«× Ÿß ‡∑à“°—∫
2.6 °“√μ√«® Õ∫ 10.20×20.95×7.35, 15.20×22.75×9.60, 12.80×21.70×8.90
„™âμ—«μ√«®«—¥™π‘¥‚ø‚쉥‚Õ¥·Õ‡√¬å∑’˧«“¡¬“« ·≈– 11×21.15×8.65 ¡‘≈≈‘‡¡μ√ (¡¡.) μ“¡≈”¥—∫ „π¢≥–∑’Ë
§≈◊Ëπ 254 π“‚π‡¡μ√ —߇°μ peak ∑’ˇ°‘¥¢÷Èπ„π‚§√¡“‚∑·°√¡ ·§≈≈— Õ“¬ÿ 2 ‡¥◊Õπ ¡’¢π“¥‡©≈’ˬ°«â“ß׬“«× Ÿß ‡∑à“°—∫
√Ÿª∑’Ë 2 14.42×23.70×7.45, 18.65×24.35×11, 16.15×22.50×8.95
·≈– 15.55×22.35×8.90 ¡¡. μ“¡≈”¥—∫ ·≈–®–‡°‘¥·§≈≈—
º≈°“√»÷°…“
‰¥â¥’¢÷Èπ ‡¡◊ËÕ¡’ chitosan 0.1 % ¢π“¥§«“¡‡¢â¡¢âπ 1 ¡°./≈.
1. °“√‡æ“–‡≈’Ȭ߷§≈≈— ‡∂“«—≈¬å‡ª√’¬ß °“√‡æ‘Ë¡ salicylic acid ¢π“¥§«“¡‡¢â¡¢âπ 150 ¡°./≈. „π
°“√„™âÕ“À“√ Ÿμ√ 43 ·≈– Ÿμ√ 43 ∑’Ë¡’ chitosan 0.1 % Õ“À“√ Ÿμ√ 43 ‡æ’¬ßÕ¬à“߇¥’¬«À√◊Õ¡’ chitosan 0.1 %
¢π“¥§«“¡‡¢â¡¢âπ 1, 3 ·≈– 5 ¡‘≈≈‘°√—¡/≈‘μ√ (¡°./≈.) ¢π“¥§«“¡‡¢â¡¢âπ 1, 3 ·≈– 5 ¡°./≈. √«¡ 4 Ÿμ√∑”„À⇰‘¥
∑”„À⇰‘¥·§≈≈— ‡æ’¬ßÕ¬à“߇¥’¬« (√Ÿª∑’Ë 3 ·≈–μ“√“ß∑’Ë 1) ·§≈≈— ‰¥â‡æ’¬ß‡≈Á°πâÕ¬·μà‡°‘¥¬Õ¥·≈–√“°‰¥â¥â«¬ (√Ÿª∑’Ë 4
‚¥¬·§≈≈— ¡’≈—°…≥–øŸ·πàπ ’‡¢’¬«ªπ ’πÈ”μ“≈‡¢â¡ ´÷Ëß ·≈–μ“√“ß∑’Ë 2, 3) ‚¥¬·§≈≈— ¡’≈—°…≥–·πàπ ’πÈ”μ“≈‡¢â¡ªπ
·§≈≈— ∑’ËÕ“¬ÿ 1 ‡¥◊Õπ ¢ÕßÕ“À“√ Ÿμ√ 43, 43+C1, 43+C3 ’‡¢’¬«·≈–¡’√“° ’πÈ”μ“≈¬“«ª√–¡“≥ 1-2 ‡´π쑇¡μ√ ·≈–
√Ÿª∑’Ë 3 · ¥ß°“√‡°‘¥·§≈≈— ¢Õ߇∂“«—≈¬å‡ª√’¬ß∫πÕ“À“√‡æ“–‡≈’È¬ß Ÿμ√ 43, 43+C1, 43+C3, 43+C5 ‡ªìπ‡«≈“ 1 ‡¥◊Õπ (A) ·≈– 2
‡¥◊Õπ (B)