Page 42 - journal-8-23-Full

34 «“√ “√°“√·æ∑¬·º “√ ‰ ¬·≈– ° √·æ ∑“ß“ ∑¬ ªï∑’Ë 9©∫—∫∑’Ë 1 ¡°√“§¡- ‘ßÀ“§¡ 2554
°“√ ∑¬åå·ºπ‰∑¬·≈–°“√·æ∑¬å∑“߇≈◊Õ°
“√°“√ ∑¬å·º ‰ ¬·≈–°“√ æ∑¬∑“å·ºπ‰∑¬·≈–°“√·æ∑¬å∑“߇≈◊Õ°
«“√ “√°“√·æ∑¬
μ“√“ß∑’Ë 6 §à“∑“߇§¡’§≈‘π‘°¢ÕßÀπŸ‡æ»‡¡’¬∑’ˉ¥â√—∫ “√ °—¥¬“‡∫≠®∑‘æ¬å‚Õ ∂ ‡ªìπ‡«≈“ 6 ‡¥◊Õπ

°≈ÿࡧ«∫§ÿ¡ °≈ÿà¡∑¥≈Õß-¢π“¥ “√ °—¥ (¡°./°°./«—π)

Õ«—¬«– πÈ”°≈—Ëπ tragacanth 10 100 500 500-R
ALT(U/L) 27.25 ± 7.69 26.33 ± 7.75 27.42 ± 10.92 24.50 ± 7.28 23.50 ± 3.45 25.33 ± 7.20
AST(U/L) 81.83 ± 12.03 83.17 ± 14.12 84.92 ± 17.72 83.33 ± 8.32 69.25 ± 4.97 74.00 ± 7.35
ALP(U/L ) 19.83 ± 3.35 19.67 ± 4.46 19.75 ± 5.01 19.58 ± 5.16 19.25 ± 7.70 19.00 ± 3.67
BUN (¡°./¥≈.) 21.29 ± 4.22 21.09 ± 3.84 20.81 ± 2.78 21.51 ± 3.46 21.08 ± 3.05 20.95 ± 3.56
§√’Õ“μ‘π‘π (¡°./¥≈.) 0.53 ± 0.15 0.50 ± 0.09 0.51 ± 0.06 0.51 ± 0.12 0.50 ± 0.07 0.49 ± 0.08
‚ª√μ’π√«¡(°./¥≈.) 6.33 ± 0.25 6.62 ± 0.40 6.58 ± 0.35 6.43 ± 0.36 6.74 ± 0.28* 6.52 ± 0.25
Õ—≈∫Ÿ¡‘π (°./¥≈.) 4.82 ± 0.19 5.03 ± 0.30 4.96 ± 0.34 4.80 ± 0.29 5.05 ± 0.26 4.88 ± 0.17
∫‘≈‘√Ÿ∫‘π (¡°./¥≈.) 0.09 ± 0.03 0.10 ± 0.04 0.09 ± 0.02 0.09 ± 0.02 0.07 ± 0.02 0.09 ± 0.02
°≈Ÿ‚§ (¡°./¥≈.) 122.42 ± 19.84 114.73 ± 19.98 109.79 ± 11.49 115.27 ± 24.95 119.90 ± 12.82 137.38 ± 28.06
°√¥¬Ÿ√‘°(¡°./¥≈.) 2.28 ± 0.69 2.18 ± 0.63 2.51 ± 0.96 2.15 ± 1.04 2.22 ± 0.67 2.32 ± 0.61
‰μ√°≈’‡´Õ‰√¥å (¡°./¥≈.) 38.70 ± 8.68 48.62 ± 19.38 42.58 ± 6.05 36.24 ± 6.47 32.96 ± 5.16 53.31 ± 36.86
§Õ‡≈ ‡μÕ√Õ≈ (¡°./¥≈.) 58.98 ± 11.03 66.15 ± 18.72 65.94 ± 16.06 61.26 ± 23.29 72.95 ± 12.98 78.78 ± 21.05
Na (mmol/l) 142.42 ± 1.00 143.00 ± 1.28 144.00 ± 1.65 143.58 ± 1.73 143.83 ± 1.80 142.83 ± 0.94
+
K (mmol/l) 7.01 ± 1.28 6.60 ± 1.09 6.85 ± 1.75 6.04 ± 1.35 6.43 ± 1.20 6.48 ± 1.01
+
Cl (mmol/l ) 107.25 ± 1.42 108.08 ± 1.62 108.17 ± 1.40 107.00 ± 1.86 106.58 ± 1.31 106.00 ± 1.41
-
§à“„πμ“√“ß· ¥ß„π√Ÿª¢Õß§à“‡©≈’ˬ ± à«π‡∫’ˬ߇∫π¡“μ√∞“π
* ·μ°μà“ß®“°°≈ÿࡧ«∫§ÿ¡¥â«¬πȔլà“ß¡’π—¬ ”§—≠∑“ß ∂‘μ‘ (p<0.05)

μË”°«à“°≈ÿࡧ«∫§ÿ¡¥â«¬πÈ”·≈– tragacanth Õ¬à“ß¡’π—¬ ”§—≠ ∑‘æ¬å‚Õ ∂·°àÀπŸ∂’∫®—°√∑“ߪ“°„π¢π“¥ 2.5, 5.0 ·≈– 10.0
ÀπŸ‡æ»ºŸâ∑’ˉ¥â√—∫ “√ °—¥¬“‡∫≠®∑‘æ¬å‚Õ ∂¢π“¥ 100 ¡°./ °./°°. · ¥ß„Àâ‡ÀÁπ«à“ “√ °—¥¬“‡∫≠®∑‘æ¬å‚Õ ∂„π¢π“¥∑’Ë
°°./«—π ¡’Õÿ∫—μ‘°“√≥å¢Õ߇´≈≈åμ—∫‡ ◊ËÕ¡·∫∫¡’‰¢¡—π Ÿß°«à“ ∑¥ Õ∫‰¡à∑”„À⇰‘¥Õ“°“√æ‘…‡©’¬∫æ≈—π·≈–‰¡à∑”„Àâ —μ«å

°≈ÿࡧ«∫§ÿ¡∑—Èß ÕßÕ¬à“ß¡’π—¬ ”§—≠ ·μà¡’Õÿ∫—μ‘°“√≥å¢Õß°“√ ∑¥≈Õß쓬 πÕ°®“°π’È “√ °—¥‰¡à∑”„À⇰‘¥°“√‡ª≈’ˬπ·ª≈ß
– ¡‰¢¡—π∑’ËμàÕ¡À¡«°‰μ™—ÈππÕ°μË”°«à“°≈ÿࡧ«∫§ÿ¡∑—Èß Õß ∑’˺‘¥ª°μ‘¢ÕßÕ«—¬«– ”§—≠„π√–¥—∫¡À欓∏‘«‘∑¬“ (gross

Õ¬à“ß¡’π—¬ ”§—≠ ÀπŸ‡æ»ºŸâ∑’ˉ¥â√—∫ “√ °—¥¢π“¥ 500 ¡°./°°./ pathology) ¢π“¥∑’Ë∑”„ÀâÀπŸ∂’∫®—°√쓬§√÷ËßÀπ÷Ëß (LD ) ¡’§à“
50
«—π·≈–°≈ÿà¡ 500-R ¡’Õÿ∫—μ‘°“√≥å°“√§—ËߢÕ߇≈◊Õ¥„πÀ≈Õ¥ ¡“°°«à“ 10.0 °./°°. ´÷Ëß Ÿß°«à“¢π“¥∑’Ë„™â„π§πª√–¡“≥ 1,000
‡≈◊Õ¥¥”∑’Ë∫√‘‡«≥√Õ¬μàÕ¢Õ߇π◊ÈÕ‰μ à«ππÕ°·≈– à«π„π Ÿß ‡∑à“

°«à“°≈ÿࡧ«∫§ÿ¡∑—Èß ÕßÕ¬à“ß¡’π—¬ ”§—≠ πÕ°®“°π’È æ∫«à“ º≈°“√»÷°…“æ‘…‡√◊ÈÕ√—ß· ¥ß„Àâ‡ÀÁπ«à“ “√ °—¥¬“‡∫≠®
°≈ÿà¡∑’ˉ¥â√—∫ “√ °—¥¢π“¥ 100 ¡°./°°./«—π ¡’°“√‡ª≈’ˬπ ∑‘æ¬å‚Õ ∂‰¡à¡’º≈μàÕ°“√‡®√‘≠‡μ‘∫‚μ °“√°‘πÕ“À“√·≈–

·ª≈ß≈—°…≥–π’È Ÿß°«à“°≈ÿࡧ«∫§ÿ¡∑’˪ÑÕπ tragacanth ÿ¢¿“æ∑—Ë«‰ª¢ÕßÀπŸ·√μ ÀπŸ‡æ»ºŸâ·≈–‡æ»‡¡’¬°≈ÿà¡∑’ˉ¥â√—∫
Õ¬à“ß¡’π—¬ ”§—≠‡™àπ°—π à«π°“√‡ª≈’ˬπ·ª≈ß∑“ß®ÿ≈欓∏‘ “√ °—¥¢π“¥ 500 ¡°./°°./«—π ¡’πÈ”Àπ—° —¡æ—∑∏å¢Õßμ—∫
«‘∑¬“Õ◊Ëπ Ê ∑’Ëæ∫„π°“√»÷°…“§√—Èßπ’È ¡’Õÿ∫—μ‘°“√≥å∑’ˉ¡à‰¥â‡æ‘Ë¡ ‡æ‘Ë¡¢÷ÈπÕ¬à“ß¡’π—¬ ”§—≠ ·μà‰¡àæ∫§«“¡º‘¥ª°μ‘¢Õß§à“‡§¡’

À√◊Õ≈¥≈ßμ“¡¢π“¥¢Õß “√ °—¥∑’ˉ¥â√—∫ (μ“√“ß∑’Ë 7 ·≈– 8) §≈‘π‘°∑’ˇ°’ˬ«¢âÕß√«¡∑—Èß√Õ¬‚√§∑“ß®ÿ≈欓∏‘«‘∑¬“∑’Ëμ—∫ ¥—ßπ—Èπ
Õ“®‡°‘¥®“°πÈ”Àπ—°μ—«∑’ËπâÕ¬°«à“°≈ÿࡧ«∫§ÿ¡∑”„À≥â§à“
«‘®“√≥å
—¡æ—∑∏å‡æ‘Ë¡¢÷Èπ ÀπŸ‡æ»ºŸâ∑’ˉ¥â√—∫ “√ °—¥¬“‡∫≠®∑‘æ¬å‚Õ ∂
º≈°“√∑¥ Õ∫æ‘…‡©’¬∫æ≈—π‚¥¬ªÑÕπ “√ °—¥¬“‡∫≠® ¢π“¥ 500 ¡°./°°./«—π ·≈–°≈ÿà¡ 500-R ¡’πÈ”Àπ—° —¡æ—∑∏å