Page 27 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 3 ฉบับที่ 1
P. 27
«“√ “√°“√·æ∑¬å·ºπ‰∑¬·≈–°“√·æ∑¬å∑“߇≈◊Õ° ªï∑’Ë Û ©∫—∫∑’Ë Ò µÿ≈“§¡ ÚıÙ˜-¡°√“§¡ ÚıÙ¯ 25
Table 4 Frequencies of volunteers with increasing cytokine levels after receiving D.
scandens
Duration
week 0 week 2 # week 4 week 6 week 8
IL-2 0/12 5/11* 4/12* 4/12* 0/12
IL-4 0/12 0/11 0/12 1/12 2/12
IL-6 0/12 7/11* 6/11*, @ 2/12 10/12*
Each value represents numbers of volunteers with increasing amount of each cytokine as
compared with the amount on week 0
# only 11 sera were tested for IL-2, IL-4 and IL-6 levels
@ only 11 sera were tested for IL-6 levels
* significantly different from initial (p < 0.05)
References
1. Muanwongyathi P, and Supatwanich P. Pharmacognostic study of Derris scandens
Benth. Mahidol University J. Pharmaceutical Science. 1981.8: 57-64.
2. Tiangburanatham W. Dictionary of Thai Medicinal Plants. Prachumtong Printing.
Bangkok: 1966.
3. Chuthaputti, A and Chavalittumrong, P. Immunomodulating activity of Derris
scandens Benth. Thai J. Pharm. Sci. 1998. 22: 137-148.
4. Sriwanthana B, and Chavalittumrong P. In vitro effect of Derris scandens on
normal lymphocyte proliferation and its activities on natural killer cells in normals
and HIV-1 infected patients. J. Ethnopharmacol 2001. 76: 125-129.
5. Chavalittumrong P, Chivapat S, Chythaputti A, Rattanajarasroj S, and Punyamong
S. Chronic toxicity study of crude extract of Derris scandens Benth. Songklanakarin
J. Sci. Technol. 199. 21: 425-433.
6. Balkwill FR, and Burke F. The cytokine network. Immunol. Today. 1989. 10:
299.
7. Waldmann TA, Dubois S. and Tagaya Y. Contrasting roles of IL-2 and IL-15 in
the life and death of lymphocytes: implications for immunotherapy. Immunity.
2001. 14: 105-110.