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Table 4 Frequencies of volunteers with increasing cytokine levels after receiving D.

scandens

Duration

week 0 week 2 # week 4 week 6 week 8

IL-2 0/12 5/11* 4/12* 4/12* 0/12
IL-4 0/12 0/11 0/12 1/12 2/12

IL-6 0/12 7/11* 6/11*, @ 2/12 10/12*

Each value represents numbers of volunteers with increasing amount of each cytokine as

compared with the amount on week 0
# only 11 sera were tested for IL-2, IL-4 and IL-6 levels
@ only 11 sera were tested for IL-6 levels

* significantly different from initial (p < 0.05)

References

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2. Tiangburanatham W. Dictionary of Thai Medicinal Plants. Prachumtong Printing.
Bangkok: 1966.
3. Chuthaputti, A and Chavalittumrong, P. Immunomodulating activity of Derris

scandens Benth. Thai J. Pharm. Sci. 1998. 22: 137-148.
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normal lymphocyte proliferation and its activities on natural killer cells in normals
and HIV-1 infected patients. J. Ethnopharmacol 2001. 76: 125-129.

5. Chavalittumrong P, Chivapat S, Chythaputti A, Rattanajarasroj S, and Punyamong
S. Chronic toxicity study of crude extract of Derris scandens Benth. Songklanakarin

J. Sci. Technol. 199. 21: 425-433.
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the life and death of lymphocytes: implications for immunotherapy. Immunity.
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