Page 26 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 3 ฉบับที่ 1

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Table 2 Blood chemistry reslts of volunteers orally given D. scandens for 8 weeks

Duration

week 0 week 2 week 4 week 6 week 8

AST (U/L) 20.91 ± 3.81 22.45 ± 4.16 20.82 ± 4.77 24.09 ± 5.17 22.91 ± 7.16
ALT (U/L) 21.64 ± 6.93 23.91 ± 9.78 25.73 ± 11.31 23.55 ± 6.83 23.64 ± 7.37

ALP (U/L) 78.45 ± 21.16 75.91 ± 20.23 74.18 ± 19.81 77.73 ± 18.45 74.18 ± 17.95
Bilirubin (mg/dL) 0.54 ± 0.19 0.63 ± 0.32 0.61 ± 0.26 0.63 ± 0.27 0.64 ± 0.27
Creatinine (mg/dL) 1.01 ± 0.13 1.04 ± 0.14* 1.05 ± 0.15 1.08 ± 0.15* 1.05 ± 0.13

BUN (mg/dL) 11.39 ± 2.51 12.14 ± 2.79 11.45 ± 2.51 12.77 ± 1.92 12.14 ± 2.19
Cholesterol (mg/dL) 201.93 ± 24.47 211.54 ± 28.05 209.56 ± 20.98 209.36 ± 26.55 210.75 ± 33.92
Triglyceride (mg/dL) 94.75 ± 41.92 76.73 ± 20.91 86.50 ± 29.56 102.12 ± 30.49 124.41 ± 53.60

Total protein (g/dL) 8.24 ± 0.33 8.20 ± 0.33 7.97 ± 0.39 8.18 ± 0.28 8.33 ± 0.29
Albumin (g/dL) 4.59 ± 0.32 4.33 ± 0.30* 4.32 ± 0.31* 4.42 ± 0.26* 4.56 ± 0.30
Uric acid (mg/dL) 5.69 ± 1.65 5.70 ± 1.60 5.71 ± 1.76 6.09 ± 1.91 6.23 ± 1.96

Glucose (mg/dL) 92.83 ± 5.47 91.87 ± 5.34 91.59 ± 6.45 93.90 ± 4.83 94.44 ± 4.39
Sodium (mmol/L) 143.00 ± 1.61 140.36 ± 1.36* 138.64 ± 1.50* 145.82 ± 2.40* 147.82 ± 3.68*
Potassium (mmol/L) 4.21 ± 0.32 4.24 ± 0.33 4.15 ± 0.19 4.25 ± 0.31 4.59 ± 0.22
Chloride (mmol/L) 106.73 ± 1.62 103.18 ± 1.60* 102.91 ± 1.58* 105.91 ± 2.66 104.73 ± 4.08

Each value represents mean ± SD
* significantly different from initial (p < 0.05)

Table 3 Immunological results of volunteers orally given D. scandens for 8 weeks

Duration

week 0 week 2 week 4 week 6 week 8

+
CD3 cells 1578 ± 314 1522 ± 380 1507 ± 410 1558 ± 349 1374 ± 327
+
CD4 cells 820 ± 184 789 ± 205 801 ± 240 822 ± 244 733 ± 214
+
CD8 cells 664 ± 167 633 ± 187 618 ± 173 646 ± 128 559 ± 134
CD4/CD8 1.30 ± 0.43 1.32 ± 0.44 1.35 ± 0.37 1.32 ± 0.46 1.35 ± 0.42

Each value represents mean + SD