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ABSTRACT

Thao-wan-priang, Derris scandens (Roxb.) Benth., has long been used in Thai
traditional medicine as diuretic, analgesic, antipyretic and muscle relaxant. The quality
standard of this crude drug has not been reported. Therefore a study was conducted on 16
samples of crude drug obtained from the Northern, Northeastern and Central parts of

Thailand. The values of total ash content, acid-insoluble ash content, water extractive, 50 %
ethanol extractive, 95 % ethanol extractive, moisture content and foaming index were given.

Chemical identification of this crude drug both by Thin-layer chromatography and
High-performance liquid chromatography was also reported. The results of this study can
be used to set up the appropriate chemical and physical specifications of Thao-wan-priang
which will be useful for quality control of this crude drug and its health products.

KEY WORDS : Thao-wan-priang, Derris scandens (Roxb.) Benth., chemical and physical
specifications, quality control, health products.

∫∑π”
‡∂“«—≈¬å‡ª√’¬ß ¡’™◊ËÕ«‘∑¬“»“ µ√å«à“ Derris scandens (Roxb.) Benth. ™◊ËÕÕ—ß°ƒ… Jewel

Vine ·≈–¡’™◊ËÕ∑âÕß∂‘Ëπµà“ßÊ ‰¥â·°à ‡∂“µ“ª≈“ ‡§√◊Õµ“ª≈“ ‡§√◊Õ‡¢“Àπ—ß (π§√√“™ ’¡“) æ“π‰ π
(1)
(2-3)
(1)
(™ÿ¡æ√) ¬à“π‡À¡“– (π§√»√’∏√√¡√“™) Õ¬Ÿà„π«ß»å Leguminosae-Papilionoideae æ◊™™π‘¥
π’ȇªìπ‰¡â‡∂“¢π“¥„À≠à „∫‡ªìπ„∫ª√–°Õ∫·∫∫¢ππ° „∫¬àÕ¬√Ÿª«ß√’ ¥Õ°™àÕÀâÕ¬≈ß ¢π“¥¢Õߥհ¬àÕ¬
‡≈Á°°«à“¥Õ°‚ π ¥Õ° ’™¡æŸÕàÕπÀ√◊Õ ’¢“« ¡’°≈‘ËπÀÕ¡ÕàÕπÊ º≈‡ªìπΩí°·∫π‡≈Á° ¡’‡¡≈Á¥ 2-4 ‡¡≈Á¥ (2)
¬“‰∑¬„™â‡∂“‡ªì𬓷°â°√–…—¬ ·°â‡ âπ‡ÕÁπ¢Õ¥ ∑”„À⇠âπÕàÕπ·≈–À¬àÕπ¥’ ¢—∫ªí “«– ·°âªí “«–æ‘°“√
‡ªìπ¬“∂à“¬‡©æ“–‡ ¡À–‡∑à“π—Èπ ‰¡à∑”„ÀâÕÿ®®“√–‡¥‘π ®÷߇À¡“–∑’Ë®–„™â„π‚√§∫‘¥ ‚√§‰Õ ‚√§À«—¥ ∫“ß·À≈àß
π‘¬¡π”‡∂“À—Ë𵓰·Àâߧ—Ë«‰ø ™ßπÈ”¥◊Ë¡·∑ππÈ”™“ „™â·°âª«¥‡¡◊ËÕ¬°≈â“¡‡π◊ÈÕ ∂â“„™â‡∂“¥Õ߇À≈â“®–‡ªìπ

¬“¢—∫√–¥Ÿ à«π√“°„™â‡∫◊ËÕª≈“ (·µà‰¡à¡’§ÿ≥ ¡∫—µ‘¶à“·¡≈ß) (2-4)
®“°°“√»÷°…“∑“߇§¡’ æ∫«à“ à«π‡∂“ (≈”µâπ) ¢Õ߇∂“«—≈¬å‡ª√’¬ß ª√–°Õ∫¥â«¬ “√‡§¡’
(5)
ª√–‡¿∑ isoflavone ·≈– isoflavone glycoside ®”π«π¡“° ‡™àπ eturunagarone , 4,4'-di-O-
(6)
(6)
(5)
methyl scandenin , lupinisol A , 5,7,4'-trihydroxy-6,8-diprenylisoflavone , 5,7,4'-
(6)
(6)
(6-7)
trihydroxy-6,3'- diprenylisoflavone , erysenegalensein E , derrisisoflavones A-F ,
(6)
(8)
(7)
(7)
scandinone , lupiniisoflavone G , lupalbigenin , derrisscandenosides A-E , 7,8-
(8)
(8)
dihydroxy-4'-methoxyisoflavone , formononetin-7-O-β-glucopyranoside , 8-hydroxy-
(8)
4',7-dimethoxyisoflavone-8-O-β-glucopyranoside , 7-hydroxy-4',8-dimethoxyisoflavone