Page 22 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 2 ฉบับที่ 3
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20  «“√ “√°“√·æ∑¬å·ºπ‰∑¬·≈–°“√·æ∑¬å∑“߇≈◊Õ°              ªï∑’Ë Ú ©∫—∫∑’Ë Û ¡‘∂ÿπ“¬π-°—𬓬π ÚıÙ˜


                                      (8)
            -7-O-β-glucopyranoside , diadzein-7-O-[α-rhamnopyranosyl-(1→6)]-β-
                                                                                          (8)
                          (8)
            glucopyranoside , formononetin-7-O-α-rhamnopyranosyl-(1→6)]-β-glucopyranoside ,
                                   (9)
            derrisscanosides A-B , genistein-7-O-[α-rhamnopyranosyl-(1→6)]-β-
                                                                     (11)
                          (8,10)
            glucopyranoside   πÕ°®“°π’È ¬—ßæ∫ 3-aryl-4-hydroxycoumarins , 4-hydroxy-3-methoxy
                        (8)
                                                                 (8)
            benzoic acid , 4-hydroxy-3,5-dimethoxybenzoic acid  ‡ªìπµâπ ·≈–æ∫ “√ª√–‡¿∑
                                                                                  (12)
            steroids ®“° à«π‡Àπ◊Õ¥‘π¢Õ߇∂“«—≈¬å‡ª√’¬ß ‡™àπ  lupeol, taraxerol ·≈– β-sitosterol   ‡ªìπµâπ
                      ”À√—∫ƒ∑∏‘Ï∑“߇¿ —™«‘∑¬“¢Õß “√ °—¥‡∂“«—≈¬å‡ª√’¬ßπ—Èπ ¡’√“¬ß“π«à“   “√ °—¥¥â«¬πÈ”
            ®“°≈”µâπ¢Õ߇∂“«—≈¬å‡ª√’¬ß¡’ƒ∑∏‘ϵâ“π°“√Õ—°‡ ∫ ‚¥¬ÕÕ°ƒ∑∏‘Ϭ—∫¬—Èß°“√ √â“ß leukotriene B ≈¥
                                                            (13)
            °“√À≈—ËߢÕß myeloperoxide ·≈–≈¥°“√ √â“ß eicosanoid  ”À√—∫ƒ∑∏‘Ï≈¥°“√Õ—°‡ ∫∑’ËÕÿâ߇∑â“ÀπŸ
            æ∫«à“‰¥âº≈¥’Õ¬à“ß¡’π—¬ ”§—≠ ‡¡◊ËÕ„™â‡ªì𬓩’¥„µâº‘«Àπ—ß ·µàƒ∑∏‘Ï≈¥°“√Õ—°‡ ∫‰¡à¡’π—¬ ”§—≠‡¡◊ËÕ
                       (13)
                                                                       (13)
            ªÑÕπ∑“ߪ“°   πÕ°®“°π’È  æ∫«à“ “√ °—¥πÈ”¡’ƒ∑∏‘ϵâ“πÕπÿ¡Ÿ≈Õ‘ √–¥â«¬  „π¢≥–∑’Ë “√ °—¥¥â«¬
            ∫‘«∏“πÕ≈·≈– “√ª√–°Õ∫ª√–‡¿∑ rhamnosyl-(1→6)-glucosylisoflavones ®“°≈”µâπ‡∂“«—≈¬å
                                      (14)
            ‡ª√’¬ß¡’ƒ∑∏‘Ï≈¥§«“¡¥—π‚≈À‘µ‰¥â  ·≈– “√ °—¥¥â«¬ 50 % ‡Õ∏“πÕ≈®“°≈”µâπ‡∂“«—≈¬å‡ª√’¬ß¡’ƒ∑∏‘Ï
                            (15)
            °√–µÿâπ   ¿Ÿ¡‘§ÿâ¡°—π   πÕ°®“°π’È ¬—ß¡’√“¬ß“π«à“ 5,7,4'-trihydroxy-6,3'-diprenylisoflavone ∑’Ë
            ·¬°‰¥â®“° “√ °—¥‡Õ∏“πÕ≈¡’ƒ∑∏‘ϵâ“π‡™◊ÈÕ√“ Trichophyton mentagrophytes ¥â«¬ ‚¥¬¡’§à“§«“¡
                                                     (6)
            ‡¢â¡¢âπµË” ÿ¥∑’ˬ—∫¬—È߇™◊ÈÕ‰¥âπâÕ¬°«à“ 15.6 ¡§°./¡≈.  ‡ªìπµâπ
                     °“√∑¥ Õ∫§«“¡‡ªìπæ‘…‡©’¬∫æ≈—π ‚¥¬°“√©’¥ “√ °—¥ 50 % ‡Õ∏“πÕ≈®“° à«π‡Àπ◊Õ¥‘π

            ‡∂“«—≈¬å‡ª√’¬ß‡¢â“∑“ß™àÕß∑âÕßÀπŸ∂’∫®—°√ æ∫«à“ ¢π“¥∑’ˇªìπæ‘…∑”„ÀâÀπŸµ“¬√âÕ¬≈– 50 §◊Õ 1 °./°°.
            ·µà‡¡◊ËÕ„Àâ‚¥¬°“√ªÑÕπ∑“ߪ“° À√◊Õ©’¥„µâº‘«Àπ—ß„π¢π“¥ 10 °./°°. °≈—∫‰¡àæ∫§«“¡‡ªìπæ‘…„¥Ê µàÕ
                     (16)
             —µ«å∑¥≈Õß   ”À√—∫°“√∑¥ Õ∫æ‘…‡√◊ÈÕ√—ßπ—Èπ ‰¡àæ∫§«“¡‡ªìπæ‘…„¥Ê „πÀπŸ∑¥≈Õß ·¡â®–„Àâ‚¥¬
                                                                                     (17)
            °“√ªÑÕπ∑“ߪ“°„π¢π“¥ Ÿß∂÷ß 600 ¡°./°°. ´÷Ë߇ªìπ¢π“¥∑’Ë Ÿß°«à“¢π“¥¬“ª°µ‘ 100 ‡∑à“  ®“°
            ¢âÕ¡Ÿ≈µà“ßÊ ¥—ß∑’ˉ¥â°≈à“«¡“·≈â« ®–‡ÀÁπ‰¥â«à“  ¡ÿπ‰æ√™π‘¥π’È¡’»—°¬¿“æ∑’Ë®–π”¡“æ—≤𓇪ìπ
            º≈‘µ¿—≥±å ÿ¢¿“æµà“ßÊ  ·≈–‡π◊ËÕß®“°¬—߉¡à¡’√“¬ß“π¥â“π¢âÕ°”Àπ¥∑“߇§¡’·≈–°“¬¿“æ¢Õß ¡ÿπ
            ‰æ√™π‘¥π’ÈÕ¬à“߇ªìπ√–∫∫¡“°àÕπ  §≥–ºŸâ«‘®—¬®÷߉¥â»÷°…“§ÿ≥¿“æ¢Õ߇∂“«—≈¬å‡ª√’¬ß∑’ˇ°Á∫®“°·À≈àß

            ∏√√¡™“µ‘µà“ßÊ ‡æ◊ËÕ„™â‡ªìπ·π«∑“ß„π°“√°”Àπ¥¡“µ√∞“π¢Õß«—µ∂ÿ¥‘∫ ´÷Ë߇ªìπ«‘∏’Àπ÷Ëß„π°“√¬°
            √–¥—∫§ÿ≥¿“æ¢Õß ¡ÿπ‰æ√‰∑¬ Ÿà¡“µ√∞“π√–¥—∫ “°≈
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