Page 28 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 16 ฉบับที่ 3

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ºŸâ√—∫º‘¥™Õ∫∫∑§«“¡: noptmc0550@gmail.com

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‰À¡¢â“«‚楇ªìπ‡»…«— ¥ÿ∑’ˇÀ≈◊Õ®“°°√–∫«π·ª√√Ÿª„πÕÿμ “À°√√¡∑’ˇ°’ˬ«°—∫¢â“«‚æ¥∑’Ë¡’Õ¬Ÿà‡ªìπ®”π«π¡“°
°“√»÷°…“π’ȇªìπ°“√»÷°…“‡ª√’¬∫‡∑’¬∫Õߧåª√–°Õ∫∑“߇§¡’ §ÿ≥§à“∑“ß‚¿™π“°“√ ƒ∑∏‘Ïμâ“πÕπÿ¡Ÿ≈Õ‘ √– ·≈–ƒ∑∏‘Ï
¬—∫¬—È߇Õπ‰´¡å‰∑‚√´‘‡π „πμ—«Õ¬à“߉À¡¢â“«‚æ¥ 3 “¬æ—π∏ÿå ‰¥â·°à ‰À¡¢â“«‚æ¥À«“π ≈—∫ ’ ‰À¡¢â“«‚æ¥
À«“π ·≈–‰À¡¢â“«‚楢⓫‡À𒬫 °“√»÷°…“Õߧåª√–°Õ∫∑“߇§¡’∑¥ Õ∫¥â«¬«‘∏’ Thin layer chromatography
phytochemical assay ‚¥¬°“√ °—¥‰À¡¢â“«‚楥⫬‡Õ∑“πÕ≈∑’˧«“¡‡¢â¡¢âπ√âÕ¬≈– 50 æ∫ “√„π°≈ÿà¡øïπÕ≈‘°
·≈–ø≈“‚«πÕ¬¥å„π “√ °—¥‰À¡¢â“«‚æ¥∑—Èß 3 “¬æ—π∏ÿå ∑”°“√»÷°…“‡ª√’¬∫‡∑’¬∫§ÿ≥§à“∑“ß‚¿™π“°“√ ¥â«¬«‘∏’
Proximate analysis æ∫«à“ ‰À¡¢â“«‚æ¥À«“π¡’ª√‘¡“≥§«“¡™◊Èπ Ÿß ÿ¥ ∑’Ë√âÕ¬≈– 10.26 ± 0.66 ‰À¡¢â“«‚楢⓫
‡À𒬫¡’ª√‘¡“≥‡∂â“ Ÿß ÿ¥ ∑’Ë√âÕ¬≈– 6.43 ± 1.77 ‰À¡¢â“«‚æ¥À«“π¡’ª√‘¡“≥‰¢¡—π Ÿß ÿ¥ ∑’Ë√âÕ¬≈– 0.29 ± 0.17
‰À¡¢â“«‚楢⓫‡À𒬫¡’ª√‘¡“≥‡ âπ„¬ Ÿß ÿ¥ ∑’Ë√âÕ¬≈– 14.13 ± 0.44 ‰À¡¢â“«‚æ¥À«“π¡’ª√‘¡“≥‚ª√μ’π Ÿß ÿ¥
∑’Ë√âÕ¬≈– 21.19 ± 0.61 ·≈–‰À¡¢â“«‚æ¥À«“π ≈—∫ ’¡’ª√‘¡“≥§“√å‚∫‰Œ‡¥√μ Ÿß ÿ¥ ∑’Ë√âÕ¬≈– 61.59 ± 1.06 ‡¡◊ËÕ
∑”°“√»÷°…“‡ª√’¬∫‡∑’¬∫ƒ∑∏‘Ïμâ“πÕπÿ¡Ÿ≈Õ‘ √– ¥â«¬«‘∏’ DPPH radical scavenging activity æ∫«à“ “√ °—¥‰À¡
¢â“«‚æ¥∑’Ë¡’§«“¡ “¡“√∂„π°“√¬—∫¬—Èߪؑ°‘√‘¬“Õπÿ¡Ÿ≈Õ‘ √– DPPH ∑’Ë√âÕ¬≈– 50 (IC ) ‰¥â¥’∑’Ë ÿ¥§◊Õ “√ °—¥‰À¡
50
¢â“«‚æ¥À«“π ´÷Ëß¡’§à“ IC Õ¬Ÿà∑’Ë 5991.98 ± 60.61 μg/ml ·≈–∑”°“√»÷°…“‡ª√’¬∫‡∑’¬∫ƒ∑∏‘Ϭ—∫¬—È߇Õπ‰´¡å‰∑‚√´‘
50
‡π ¥â«¬«‘∏’ Tyrosinase inhibition activity æ∫«à“ “√ °—¥‰À¡¢â“«‚æ¥∑’Ë “¡“√∂¬—∫¬—Èß °“√∑”ß“π¢Õ߇Õπ‰´¡å
‰∑‚√´‘‡π ∑’Ë√âÕ¬≈– 50 (IC ) ‰¥â¥’∑’Ë ÿ¥ §◊Õ “√ °—¥‰À¡¢â“«‚楢⓫‡À𒬫 ´÷Ëß¡’§à“ IC Õ¬Ÿà∑’Ë 3082.28 ±
50
50
347.98 μg/ml °“√»÷°…“π’È· ¥ßº≈°“√«‘‡§√“–Àå§ÿ≥§à“∑“ß‚¿™π“°“√ ƒ∑∏‘Ïμâ“πÕπÿ¡Ÿ≈Õ‘ √– ·≈–ƒ∑∏‘Ϭ—∫¬—È߇Õπ‰´¡å
‰∑‚√´‘‡π ´÷Ëß “¡“√∂π”º≈∑’ˉ¥â‰ª‡ªìπ¢âÕ¡Ÿ≈æ◊Èπ∞“π ”À√—∫æ—≤π“º≈‘μ¿—≥±å∑’Ë„™â¥Ÿ·≈ ÿ¢¿“æ·≈–æ—≤𓇪ìπ
º≈‘μ¿—≥±å‡§√◊ËÕß ”Õ“ß∑’Ë∑”„À⺑«¢“«‰¥âμàÕ‰ª
§” ”§—≠: ‰À¡¢â“«‚æ¥ §ÿ≥§à“∑“ß‚¿™π“°“√ ƒ∑∏‘Ïμâ“πÕπÿ¡Ÿ≈Õ‘ √– ƒ∑∏‘Ϭ—∫¬—È߇Õπ‰´¡å‰∑‚√´‘‡π

Received date 16/02/18 Accepted date 06/11/18

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