Page 30 - journal-7-2-S-Full

Journal of Thai Traditional & Alternative Medicine Vol. 7 No. 2 May-August (Supplement) 2009 ÚÒ

INDONESIA

Identification of Components of Essential oil from Cananga odorata which

Penetrated into the Rat Skin (Wistar Strain) in the Practice of Timung (Devel-

opment of Timung as Alternative Healing)

1 2
Mangestuti Agil , Esti Hendradi1, Budiastuti
1
Faculty of Pharmacy, Airlangga University , Surabaya- Indonesia
2
Production Manager of PT. Heptasari Unggul Surabaya- Indonesia.

Components of essential oil of cananga flowers (Cananga odorata) from Indonesia had been studied for

their penetration ability into the skin of rat (Wistar strain) in the practice of Timung using modified Timung
apparatus.
Components which penetrated into the rat skin were determined using Gas Chromatography Mass Spec-

trometry (GC-MS) and identified as p-methyl-anisole, Linalool-L, geraniol, eugenol, neril-asetat, trans-(β)-
caryophyllene, (+)-aromadendrene, α-humulen, α-amorphen, germacrene D, Germacrene B, (Z, E)-α-farnesen,
Δ-cadinene.

Components which penetrated into the receptor phase (buffer phase) are p-methyl-anisol, linalool-L, trans-
geraniol, eugenol, benzyl alcohol, trans-caryophyllene, α-humulene, germacrane-D, (Z, E)-α-farnesen, Δ-cadinene.

It can be concluded that components of Cananga Oil showed the ability to penetrate into the skin in the
practice of Timung.
Key words: Cananga odorata, essential oil, rat skin, timung